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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2071-8713-5065</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-5065</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Гиперфагия и ожирение</article-title><trans-title-group xml:lang="en"><trans-title>Hyperphagia and obesity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Yalochkina</surname><given-names>T O</given-names></name></name-alternatives><email xlink:type="simple">tatiana540@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Pigarova</surname><given-names>E A</given-names></name></name-alternatives><email xlink:type="simple">kpigarova@gmail.com</email></contrib></contrib-group><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2013</year></pub-date><volume>10</volume><issue>1</issue><issue-title>№1 (2013)</issue-title><fpage>14</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Yalochkina T.O., Pigarova E.A., 2013</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="ru">Yalochkina T.O., Pigarova E.A.</copyright-holder><copyright-holder xml:lang="en">Yalochkina T.O., Pigarova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/5065">https://www.omet-endojournals.ru/jour/article/view/5065</self-uri><abstract><p>С давних времен человечество сталкивается с проблемой ожирения, вызванного несоответствием между поступающей в организм и используемой энергией. В последние десятилетия, как среди женщин, так и среди мужчин наблюдается эпидемия ожирения, возникновение которой можно объяснить повышенным употреблением высококалорийных и богатых жиром продуктов. Существует несколько причин повышенного употребления калорийных продуктов, которые рассматриваются в данной лекции. В статье также освещаются механизмы, лежащие в основе гиперфагических расстройств, и заболевания, основным проявлением которых является неутолимое чувство голода.</p></abstract><trans-abstract xml:lang="en"><p>Since ancient times, mankind is faced with the problem of obesity, caused by mismatch between energy intake and energy use. In recent decades, both women and men are involved in obesity epidemic, the occurrence of which can be attributed to the increased consumption of energy – and fat-rich foods. There are several reasons for the increased consumption of high-calorie foods that are discussed in this paper. The article also highlights the mechanisms underlying hyperphagic disorders and diseases, the main manifestation of which is the insatiable hunger.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>гиперфагия</kwd><kwd>синдром Прадера-Вилли</kwd><kwd>гипоталамический синдром</kwd><kwd>дофамин</kwd><kwd>грелин</kwd><kwd>лептин</kwd><kwd>аппетит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>hyperphagia</kwd><kwd>Prader-Willi syndrome</kwd><kwd>hypothalamic syndrome</kwd><kwd>dopamine</kwd><kwd>ghrelin</kwd><kwd>leptin</kwd><kwd>appetite</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bereket A, Kiess W, Lustig RH, Muller HL, Goldstone AP, Weiss R, Yavuz Y, Hochberg Z.Hypothalamic obesity in children. 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