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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2071-8713-4953</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-4953</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Функциональное состояние почек у детей и подростков с ожирением</article-title><trans-title-group xml:lang="en"><trans-title>Funktsional'noe sostoyanie pochek u detey i podrostkov s ozhireniem</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Gaysina</surname><given-names>L R</given-names></name></name-alternatives><email xlink:type="simple">leilag@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Safina</surname><given-names>A I</given-names></name></name-alternatives><email xlink:type="simple">safina_asia@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Valeeva</surname><given-names>Farida Vadutovna</given-names></name></name-alternatives><email xlink:type="simple">val_farida@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГОУ ВПО Казанский государственный медицинский университет Росздрава, Казань</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan State Medical Univarsity</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2011</year></pub-date><volume>8</volume><issue>2</issue><issue-title>№2 (2011)</issue-title><fpage>52</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Gaysina L.R., Safina A.I., Valeeva F.V., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Gaysina L.R., Safina A.I., Valeeva F.V.</copyright-holder><copyright-holder xml:lang="en">Gaysina L.R., Safina A.I., Valeeva F.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/4953">https://www.omet-endojournals.ru/jour/article/view/4953</self-uri><abstract><p>В современном обществе избыточная масса тела и ожирение являются одними из самых актуальных проблем. Количество пациентов, имеющих избыточный вес, неуклонно растет и, по некоторым данным, удваивается каждые три десятилетия. Ожирение патогенетически связано с несколькими факторами сердечно-сосудистого риска, такими как сахарный диабет и артериальная гипертензия, которые часто приводят к поражению почек; ожирение же само по себе связано с неблаго-приятной почечной гемодинамикой, которая независимо от данных факторов может вносить свой вклад в патологию почек. В нашей работе мы изучали влияние избыточной массы тела и ожирения у детей и подростков на функцию канальцевого аппарата почек и скорость клубочковой фильтрации.</p></abstract><trans-abstract xml:lang="en"><p>Overweight and obesity are the most actual problems nowadays. Number of overweight patients steadily raises and duplicates every three decades. Obesity is associated with some factors of cardiovascular risk like diabetes mellitus and arterial hypertension, frequently leads to kidney disfunction. Obesity itself can result in poor renal hemodynamics, well-known risk factor of kidney disease. We studied impact of overweight and obesity in children and adolescents on renal tubular function and glomerular filtration rate.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>дети</kwd><kwd>состояние почек</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>children</kwd><kwd>kidney function</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Петеркова В.А. Руководство по детской cэндокринологии. - М., 2006. - 600 с.</mixed-citation><mixed-citation xml:lang="en">Дедов И.И., Петеркова В.А. Руководство по детской cэндокринологии. - М., 2006. - 600 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Тареева И.Е. Нефрология / Руководство для врачей. - М., 2000. - 689 с.</mixed-citation><mixed-citation xml:lang="en">Тареева И.Е. Нефрология / Руководство для врачей. - М., 2000. - 689 с.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Федорова Е.Ю., Кутырина И.М. Механизмы прогрессирования поражения почек при ожирении // Нефрология и диализ. - 2006. - Т. 8, №2. - С. 102-111.</mixed-citation><mixed-citation xml:lang="en">Федорова Е.Ю., Кутырина И.М. Механизмы прогрессирования поражения почек при ожирении // Нефрология и диализ. - 2006. - Т. 8, №2. - С. 102-111.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Afshinnia F., Wilt T.J., Duval S. et al. Weight loss and proteinuria: systematic review of clinical trials and comparative cohorts // Nephrology, Dialysis, Transplantation: Official Publication Of The European Dialysis And Transplant Association - European Renal Association [Nephrol Dial Transplant]. - 2010 Apr. - Vol. 25 (4). - Р. 1173-83. Date of Electronic Publication: 2009 Nov 27.</mixed-citation><mixed-citation xml:lang="en">Afshinnia F., Wilt T.J., Duval S. et al. Weight loss and proteinuria: systematic review of clinical trials and comparative cohorts // Nephrology, Dialysis, Transplantation: Official Publication Of The European Dialysis And Transplant Association - European Renal Association [Nephrol Dial Transplant]. - 2010 Apr. - Vol. 25 (4). - Р. 1173-83. Date of Electronic Publication: 2009 Nov 27.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bosma R.J., Krikken J.A., Homan van der Heide J.J., et al. Obesity and renal hemodynamics // Contributions To Nephrology [Contrib Nephrol]. - 2006. - Vol. 151. - Р. 184-202.</mixed-citation><mixed-citation xml:lang="en">Bosma R.J., Krikken J.A., Homan van der Heide J.J., et al. Obesity and renal hemodynamics // Contributions To Nephrology [Contrib Nephrol]. - 2006. - Vol. 151. - Р. 184-202.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chen B., Yang D., Chen Y., et al. The prevalence of microalbuminuria and its relationships with the components of metabolic syndrome in the general population of China // International Journal Of Clinical Chemistry [Clin Chim Acta]. - 2010, May 2. - Vol. 411 (9-10). - Р. 705-9. Date of Electronic Publication: 2010 Feb 04.</mixed-citation><mixed-citation xml:lang="en">Chen B., Yang D., Chen Y., et al. The prevalence of microalbuminuria and its relationships with the components of metabolic syndrome in the general population of China // International Journal Of Clinical Chemistry [Clin Chim Acta]. - 2010, May 2. - Vol. 411 (9-10). - Р. 705-9. Date of Electronic Publication: 2010 Feb 04.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Drechsler C., Grootendorst D.C., Boeschoten E.W., et al. Changes in parathyroid hormone, body mass index and the association with mortality in dialysis patients // Nephrol Dial Transplant. - 2010 Sep 14. [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">Drechsler C., Grootendorst D.C., Boeschoten E.W., et al. Changes in parathyroid hormone, body mass index and the association with mortality in dialysis patients // Nephrol Dial Transplant. - 2010 Sep 14. [Epub ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Fukumoto S. Disorders of phosphate metabolism // Rinsho Byori. - 2010 Mar. - № 58(3). - Р. 225-31.</mixed-citation><mixed-citation xml:lang="en">Fukumoto S. Disorders of phosphate metabolism // Rinsho Byori. - 2010 Mar. - № 58(3). - Р. 225-31.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">García-Cantón C., Bosch E., Auyanet I., et al. [25 hydroxyvitamin D levels and cardiovascular risk in a cohort of patients with advanced chronic kidney disease] // Nefrologia. - 2010. - № 30(4). - Р. 435-42. doi: 10.3265/Nefrologia. pre2010.Mar.10288.</mixed-citation><mixed-citation xml:lang="en">García-Cantón C., Bosch E., Auyanet I., et al. [25 hydroxyvitamin D levels and cardiovascular risk in a cohort of patients with advanced chronic kidney disease] // Nefrologia. - 2010. - № 30(4). - Р. 435-42. doi: 10.3265/Nefrologia. pre2010.Mar.10288.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Guarnieri G., Zanetti M., Vinci P., et al. Metabolic syndrome and chronic kidney disease // J Ren Nutr. - 2010 Sep. - № 20(5 Suppl). - S19-23.</mixed-citation><mixed-citation xml:lang="en">Guarnieri G., Zanetti M., Vinci P., et al. Metabolic syndrome and chronic kidney disease // J Ren Nutr. - 2010 Sep. - № 20(5 Suppl). - S19-23.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hultin H., Edfeldt K., Sundbom M., Hellman P. Left-shifted relation between calcium and parathyroid hormone in obesity // J Clin Endocrinol Metab. - 2010 Aug. - № 95(8). - Р. 3973-81. Epub 2010 Jun 2.</mixed-citation><mixed-citation xml:lang="en">Hultin H., Edfeldt K., Sundbom M., Hellman P. Left-shifted relation between calcium and parathyroid hormone in obesity // J Clin Endocrinol Metab. - 2010 Aug. - № 95(8). - Р. 3973-81. Epub 2010 Jun 2.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kopple J.D. Obesity and chronic kidney disease // J Ren Nutr. - 2010 Sep. - № 20(5 Suppl). - S29-30.</mixed-citation><mixed-citation xml:lang="en">Kopple J.D. Obesity and chronic kidney disease // J Ren Nutr. - 2010 Sep. - № 20(5 Suppl). - S29-30.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Praga M., Morales E. Obesity-related renal damage: changing diet to avoid progression // Kidney Int. - 2010 Oct. - № 78(7). - Р. 633-5.</mixed-citation><mixed-citation xml:lang="en">Praga M., Morales E. Obesity-related renal damage: changing diet to avoid progression // Kidney Int. - 2010 Oct. - № 78(7). - Р. 633-5.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Saland J.M., Pierce C.B., Mitsnefes M.M., et al. Dyslipidemia in children with chronic kidney disease // Kidney Int. - 2010 Aug 25. [Epub ahead of print].</mixed-citation><mixed-citation xml:lang="en">Saland J.M., Pierce C.B., Mitsnefes M.M., et al. Dyslipidemia in children with chronic kidney disease // Kidney Int. - 2010 Aug 25. [Epub ahead of print].</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Siew E.D., Ikizler T.A. Insulin resistance and protein energy metabolism in patients with advanced chronic kidney disease // Semin Dial. - 2010 Jul-Aug. - № 23(4). - Р. 378-82.</mixed-citation><mixed-citation xml:lang="en">Siew E.D., Ikizler T.A. Insulin resistance and protein energy metabolism in patients with advanced chronic kidney disease // Semin Dial. - 2010 Jul-Aug. - № 23(4). - Р. 378-82.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Vaziri N.D. Lipotoxicity and impaired high density lipoprotein-mediated reverse cholesterol transport in chronic kidney disease // J Ren Nutr. - 2010 Sep. - № 20(5 Suppl). - S35-43.</mixed-citation><mixed-citation xml:lang="en">Vaziri N.D. Lipotoxicity and impaired high density lipoprotein-mediated reverse cholesterol transport in chronic kidney disease // J Ren Nutr. - 2010 Sep. - № 20(5 Suppl). - S35-43.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
