ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/2071-8713-4948ometendo-4948Research ArticleСтатьиArticlesКоррекция артериальной гипертонии у больных сахарным диабетом 2 типа: фокус на жесткость артерийKorrektsiya arterial'noy gipertonii u bol'nykh sakharnym diabetom 2 tipa: fokus na zhestkost' arteriyVikulovaOlga Konstantinovna

к.м.н., ведущий научный сотрудник

olga-vikulova-1973@yandex.ruФГБУ "Эндокринологический научный центр" Минздравсоцразвития России, МоскваРоссияEndocrinology Research Centre, MoscowRussian Federation20111506201182№2 (2011)1925Copyright © Vikulova O.K., 20112011Vikulova O.K.Vikulova O.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/4948

Повышение жесткости артерий является одним из мощных патогенетических факторов, ассоциированных с высоким риском сердечно-сосудистых осложнений и смертности пациентов с сахарным диабетом 2-го типа (СД2) и метаболическим синдромом. Коррекция жесткости артерий имеет приоритетное значение для снижения риска прогрессирования атеросклероза и органопротекции. Терапия ингибиторами АПФ (Амприлан) обеспечивает не только высокий антигипертензивный эффект, но и достоверное улучшение параметров, характеризующих жесткость артерий, что свидетельствует о дополнительном вазопротективном действии этого препарата.

Elevation of the arterial stiffness is one of the important pathogenic factors associated with a high risk of cardiovascular complications and mortality rate in patients with diabetes and metabolic syndrome. Correction of the arterial stiffness has a great value for decrease of the risk of atherosclerosis progress and organ protection. Therapy with ACE inhibitor ramipril provides not only high antihypertensive effect but also significant improvement of parameters of the arterial stiffness which indicates an additional vasoprotective effect of the drug.

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The authors declare that there are no conflicts of interest present.