ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/2071-8713-4938ometendo-4938Research ArticleСтатьиArticlesСердце и ожирениеSerdtse i ozhirenieDedovI I-AleksandrovAn A-KukharenkoS S-20061503200631№1 (2006)1420Copyright © Dedov I.I., Aleksandrov A.A., Kukharenko S.S., 20062006Dedov I.I., Aleksandrov A.A., Kukharenko S.S.Dedov I.I., Aleksandrov A.A., Kukharenko S.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/4938ReferencesPoirier P., Eckel RH. The heart and obesity. In:Fuster V. Alexander RW, King S., et al eds Hursts The Heart. New York, NY:McGraw-Hill. 2000:2289-2303.Poirier P., Eckel RH. The heart and obesity. In:Fuster V. Alexander RW, King S., et al eds Hursts The Heart. New York, NY:McGraw-Hill. 2000:2289-2303.Alpert M.A. Obesity cardiomyopathy:pathophysiology and evolution of the clinical syndrome. Am J Med Sci. 2001;321:225-236.Alpert M.A. Obesity cardiomyopathy:pathophysiology and evolution of the clinical syndrome. Am J Med Sci. 2001;321:225-236.Rossel S., Belfrage E. Blood circulation in adipose tissue. Physiol. Rev. 1979;59:1078-1104.Rossel S., Belfrage E. Blood circulation in adipose tissue. Physiol. Rev. 1979;59:1078-1104.Alexander JK, Alpert MA. Hemodynamic alterations with obesity in man. In: Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:45-46.Alexander JK, Alpert MA. Hemodynamic alterations with obesity in man. In: Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:45-46.Alexander JK, Dennis EW, Smith WG, et al. Blood volume, cardiac output and distribution of systemic blood flow in extreme obesity. Cardiovasc. Res Center Bull. 1962;1:39-44.Alexander JK, Dennis EW, Smith WG, et al. Blood volume, cardiac output and distribution of systemic blood flow in extreme obesity. Cardiovasc. Res Center Bull. 1962;1:39-44.Alexander JK. Obesity and cardiac performance. Am J Cardiol. 1964;14:860-865.Alexander JK. Obesity and cardiac performance. Am J Cardiol. 1964;14:860-865.DeDivitiis O, Fazio S, Petitto M et al Obesity and cardiac function. Circulation. 1981;64:477-489.DeDivitiis O, Fazio S, Petitto M et al Obesity and cardiac function. Circulation. 1981;64:477-489.Backman L, Freyschuss U., Hallberg D. et al. Cardiovascular function in extreme obesity. Acta Med Scand. 1973;193:437-446.Backman L, Freyschuss U., Hallberg D. et al. Cardiovascular function in extreme obesity. Acta Med Scand. 1973;193:437-446.Kasper EK, Hruban RH, Baughman KL. Cardiomyopathy of obesity. A clinical pathologic evaluation of 43 obese pts with heart failure. Am J Cardiol. 1992;70:921-924.Kasper EK, Hruban RH, Baughman KL. Cardiomyopathy of obesity. A clinical pathologic evaluation of 43 obese pts with heart failure. Am J Cardiol. 1992;70:921-924.Messerli FH, Christie B, DeCarvalho JGR et al Obesity and essential hypertenion. Hemodynamics, intravascular volume, sodium excretion and plasma rennin activity, Arch Intern Med. 1981;141:81-85.Messerli FH, Christie B, DeCarvalho JGR et al Obesity and essential hypertenion. Hemodynamics, intravascular volume, sodium excretion and plasma rennin activity, Arch Intern Med. 1981;141:81-85.Alpert MA, Alexander JK, Cardiac morphology and obesity in man. In:Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:25-44.Alpert MA, Alexander JK, Cardiac morphology and obesity in man. In:Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:25-44.Stamler R., Stamler J., Riedlinger W. Et al. Weight and blood pressure. Findings in hypertension screening of 1 million Americans. J. Am. Med. Assoc. 1978;240:1607-1611.Stamler R., Stamler J., Riedlinger W. Et al. Weight and blood pressure. Findings in hypertension screening of 1 million Americans. J. Am. Med. Assoc. 1978;240:1607-1611.Van Itallie ТВ., Health imnplications of overweight and obesity in the United States. Ann Intern. Med. 1985;103:983-988.Van Itallie ТВ., Health imnplications of overweight and obesity in the United States. Ann Intern. Med. 1985;103:983-988.Alpert MA, Alexander JK. Obesity and ventricular function in man:systolic function. In:Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:77-94.Alpert MA, Alexander JK. Obesity and ventricular function in man:systolic function. In:Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:77-94.Alpert MA, Terry BE, Lambert CR et al. Factors influenceing left ventricular systolic finction in non-hypertensive morbidly obese pts, and effect of weight loss induced by gastroplasty. Am J Cardiol. 1993;71:733-737.Alpert MA, Terry BE, Lambert CR et al. Factors influenceing left ventricular systolic finction in non-hypertensive morbidly obese pts, and effect of weight loss induced by gastroplasty. Am J Cardiol. 1993;71:733-737.Chakko S, Alpert MA, Alexander JK. Obesity and ventricular function in man:diastolic function. In:Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:57-76.Chakko S, Alpert MA, Alexander JK. Obesity and ventricular function in man:diastolic function. In:Alpert MA Alexander JK eds. The heart and Lung in Obesity, Armonk, NY, Futura 1998:57-76.Alexander JK, Alpert MA. Pathogenesis and clinical manifistations of obesity cardiomyopathy In:Alpert M.A., Alexander JK, eds. The heart and lung in obesity. Armonk, NY:Futura, 1998:133-146.Alexander JK, Alpert MA. Pathogenesis and clinical manifistations of obesity cardiomyopathy In:Alpert M.A., Alexander JK, eds. The heart and lung in obesity. Armonk, NY:Futura, 1998:133-146.Alexander J., Woodard C, Quinones MA, Gaash WH. Heart Failure from obesity. In Medical Complications of obesity, edited by Manchini M., Lewis B. Contaldo F. London, Academic press, 1978:179-187.Alexander J., Woodard C, Quinones MA, Gaash WH. Heart Failure from obesity. In Medical Complications of obesity, edited by Manchini M., Lewis B. Contaldo F. London, Academic press, 1978:179-187.Estes EH, Sieker HO, Mcintosh HD, et al. Reversible cardiopulmonary syndrome with extreme obesity. Circulation. 1957;41:179-187.Estes EH, Sieker HO, Mcintosh HD, et al. Reversible cardiopulmonary syndrome with extreme obesity. Circulation. 1957;41:179-187.Alpert MA, Terry BE, Lambert CR et al. Cardiac morphology and left ventricular finction in morbidly obese pts with and without congestive heart failure and effct of weight loss. Am J Cardiol. 1997;80:736-740.Alpert MA, Terry BE, Lambert CR et al. Cardiac morphology and left ventricular finction in morbidly obese pts with and without congestive heart failure and effct of weight loss. Am J Cardiol. 1997;80:736-740.Backman L, Freyschuss U., Hallberg D et al. Reversibility of cardiovascular changes in extreme obesity. Effects of weight reduction through jejunoileostomy. Acta Med Scand 1979;205:367-373.Backman L, Freyschuss U., Hallberg D et al. Reversibility of cardiovascular changes in extreme obesity. Effects of weight reduction through jejunoileostomy. Acta Med Scand 1979;205:367-373.Gottdiener JS, Reda DJ, Materson BJ et al. Importance of obesity, race and age to the cardiac structural and functional effects of hypertension. J Am Coll Card. 1994;24:1492-1498.Gottdiener JS, Reda DJ, Materson BJ et al. Importance of obesity, race and age to the cardiac structural and functional effects of hypertension. J Am Coll Card. 1994;24:1492-1498.Lauer MS, Anderson KM, Kannel WB, Levy D. The impactof obesity on left ventricular mass and geometry. The Framingham Heart Study. JAMA. 1991;266:231-236.Lauer MS, Anderson KM, Kannel WB, Levy D. The impactof obesity on left ventricular mass and geometry. The Framingham Heart Study. JAMA. 1991;266:231-236.Post WS, Levy D. New developments in the epidemiology of left ventricular hypertrophy . Curr Opin Cardiol. 1994;9;534-541.Post WS, Levy D. New developments in the epidemiology of left ventricular hypertrophy . Curr Opin Cardiol. 1994;9;534-541.De Divitus, S. Fazio, M. Petitto, G. Maddalena, F. Contaldo, M. Mancini. Obesity and cardiac function. Circulation. 1981; 64(3):477-481.De Divitus, S. Fazio, M. Petitto, G. Maddalena, F. Contaldo, M. Mancini. Obesity and cardiac function. Circulation. 1981; 64(3):477-481.Bella JN, Devereux RB, Roman MJ et al. Relations of left ventricular mass to fatfree and adipose body mass :the strong heart study. Circulation. 1998;98:2538-2544.Bella JN, Devereux RB, Roman MJ et al. Relations of left ventricular mass to fatfree and adipose body mass :the strong heart study. Circulation. 1998;98:2538-2544.Kuch В., Hense HW, Gheiting В. et al. Body composition and prevalence of left ventricular hypertrophy. Circulation. 2000;102:405-410.Kuch В., Hense HW, Gheiting В. et al. Body composition and prevalence of left ventricular hypertrophy. Circulation. 2000;102:405-410.Prentice AM, Goldberg GR, Jabb SA et al. Physiological responses to slimming. Proc Nutr Soc. 1991;50:441-458.Prentice AM, Goldberg GR, Jabb SA et al. Physiological responses to slimming. Proc Nutr Soc. 1991;50:441-458.Taylor CR, Weibel ER. Design of mammalian respiratory system and strategy. Resp. Physiol. 1981;44:1-10.Taylor CR, Weibel ER. Design of mammalian respiratory system and strategy. Resp. Physiol. 1981;44:1-10.Alpert N., Alexander J. The heart and lung in obesity. Armonk, NY: Future Publishing, 1998.Alpert N., Alexander J. The heart and lung in obesity. Armonk, NY: Future Publishing, 1998.Porter LE., Hollenberg NK. Obesity, salt intake and renal perfusion in healthy humans. Hypertension. 1998;32:144-148.Porter LE., Hollenberg NK. Obesity, salt intake and renal perfusion in healthy humans. Hypertension. 1998;32:144-148.Bloomgarden Z. Obesity, Hypertension and insulin resistance. Diabetes Care. 2002;25(11):2088-2097.Bloomgarden Z. Obesity, Hypertension and insulin resistance. Diabetes Care. 2002;25(11):2088-2097.Kuo J, Barret-Jones O., Hall J. Chronic cardiovascular and renal actions of leptin during hyperinsulinaemia. Am J Physiol Regul Integr Comp Physiol. 2003;284:R1037-R1042.Kuo J, Barret-Jones O., Hall J. Chronic cardiovascular and renal actions of leptin during hyperinsulinaemia. Am J Physiol Regul Integr Comp Physiol. 2003;284:R1037-R1042.Xavier Pi-Sunyer F. The Obesity Epidemic:Pethophysiology and consequences of obesity. Obesity Research. 2002;10(Suppl. 2):97s-104s.Xavier Pi-Sunyer F. The Obesity Epidemic:Pethophysiology and consequences of obesity. Obesity Research. 2002;10(Suppl. 2):97s-104s.Александров Ан.А., Поддубская Е.А., Кухаренко С.С., Волкова Н.Г., Оганов Р.Г. Геометрия левого желудочка, артериальная гипертония и ожирение:поиск новых путей профилактики. Профилактика заболеваний и укрепление здоровья. М.: Медиасфера, 2003. 5. С. 6-11.Александров Ан.А., Поддубская Е.А., Кухаренко С.С., Волкова Н.Г., Оганов Р.Г. Геометрия левого желудочка, артериальная гипертония и ожирение:поиск новых путей профилактики. Профилактика заболеваний и укрепление здоровья. М.: Медиасфера, 2003. 5. С. 6-11.Avellone G., Di Garbo V., Cordova R., Raneli G., De Simone R., Bompiani G. Coagulation, fibrinolysis and haemorheology in premenopausal obese women with different body fat distribution. Thromb. Res. 1994;75:223-231.Avellone G., Di Garbo V., Cordova R., Raneli G., De Simone R., Bompiani G. Coagulation, fibrinolysis and haemorheology in premenopausal obese women with different body fat distribution. Thromb. Res. 1994;75:223-231.Alpert MA, Hashimi M. Obesity and the heart. Am J Med Sci. 1993;306:117-123.Alpert MA, Hashimi M. Obesity and the heart. Am J Med Sci. 1993;306:117-123.Wirth A., Sharma AM., Schunkert H. Kardiomyopathie bei Adipositas - eine Krankheitsentitat? Dtsch Med Wochenschr. 2000;125:944-949.Wirth A., Sharma AM., Schunkert H. Kardiomyopathie bei Adipositas - eine Krankheitsentitat? Dtsch Med Wochenschr. 2000;125:944-949.Bella JN, Devereux RB, Roman MJ et al. Relations of left ventricular mass to fatfree and adipose body mass :the strong heart study. Circulation. 1998;98:2538-2544.Bella JN, Devereux RB, Roman MJ et al. Relations of left ventricular mass to fatfree and adipose body mass :the strong heart study. Circulation. 1998;98:2538-2544.Hense HW, Gheiting В., Muscholl M et al. The associations of body size and body composition with left ventricular mass:impacts for indexation in adults. J Am Coll Cardiol. 1998;32:451-457.Hense HW, Gheiting В., Muscholl M et al. The associations of body size and body composition with left ventricular mass:impacts for indexation in adults. J Am Coll Cardiol. 1998;32:451-457.Kuch В., Muscholl M., Luchner A. et al. Gender specific differences in left ventricular adaptation to obesity and hypertension. J Hum Hypertens. 1998;12:685-691.Kuch В., Muscholl M., Luchner A. et al. Gender specific differences in left ventricular adaptation to obesity and hypertension. J Hum Hypertens. 1998;12:685-691.Amad K., Brennan J., Alexander J. The Cardiac pathology of chronic Exogenous Obesity. Circulation. 1965;22:740-745.Amad K., Brennan J., Alexander J. The Cardiac pathology of chronic Exogenous Obesity. Circulation. 1965;22:740-745.Davy K., Hall J. Obesity and hypertension:two epidemics or one? Am J Physiol. Regul Integr Comp Physiol. 2004;286:R803-R813.Davy K., Hall J. Obesity and hypertension:two epidemics or one? Am J Physiol. Regul Integr Comp Physiol. 2004;286:R803-R813.Bloomgarden Z. Adiposity and Diabetes. Diabetes Care. 2002;25:2342-2349.Bloomgarden Z. Adiposity and Diabetes. Diabetes Care. 2002;25:2342-2349.Counihan TB. Heart failure due to extreme obesity. Br. Heart J. 1956;18:425.Counihan TB. Heart failure due to extreme obesity. Br. Heart J. 1956;18:425.Alexander JK, Pettigrove J. Obesity and congestive heart failure. Geriatrics. 1967;22:101.Alexander JK, Pettigrove J. Obesity and congestive heart failure. Geriatrics. 1967;22:101.AlexanderJ., Woodard C., Quinones MA., Gaash WH. Heart Failure from obesity. In Medical Complications of obesity< edited by Manchini M., Lewis B. Contaldo F. London, Academic press, 1979:243.AlexanderJ., Woodard C., Quinones MA., Gaash WH. Heart Failure from obesity. In Medical Complications of obesity< edited by Manchini M., Lewis B. Contaldo F. London, Academic press, 1979:243.Galinier M., Pathak A., Roncalli J., Massabuau P. Obesity and cardiac failure. Arch Mal Coeur Vaiss. 2005 Jan 98(1):39-45.Galinier M., Pathak A., Roncalli J., Massabuau P. Obesity and cardiac failure. Arch Mal Coeur Vaiss. 2005 Jan 98(1):39-45.Kenchaiah S, Evans J, Levy D. et al. Obesity and the risk of heart failure. N Engl J Med. 2002;347:305-313.Kenchaiah S, Evans J, Levy D. et al. Obesity and the risk of heart failure. N Engl J Med. 2002;347:305-313.Smith HL, Willis F. Adiposity of the heart. Arch. Int. Med. 1933;52:911.Smith HL, Willis F. Adiposity of the heart. Arch. Int. Med. 1933;52:911.Hubert H.B., Feinleib M., McNamara PM. et al. Obesity as an indepedent risk factor for cardiovascular desease. A 26 year follow up of participants in the Framingham heart study. Circulation. 1983;67:968-977.Hubert H.B., Feinleib M., McNamara PM. et al. Obesity as an indepedent risk factor for cardiovascular desease. A 26 year follow up of participants in the Framingham heart study. Circulation. 1983;67:968-977.
The authors declare that there are no conflicts of interest present.