References

ometendo

Ожирение и метаболизм

Obesity and metabolism

2071-87132306-5524

Endocrinology Research Centre

10.14341/omet13290

ometendo-13290

Research Article

ОБЗОРЫ

REVIEWS

Минеральные нарушения у пациентов с хроническими заболеваниями печени. Часть 2: диагностика

Mineral disorders in patients with chronic liver disease. Part 2: management

https://orcid.org/0009-0009-6630-5871

Спасская

О. Ю.

Spasskaya

O. Yu.

Спасская Ольга Юрьевна

115478, Москва, ул. Дм. Ульянова, д. 11

Scopus ID: 57226518518

Olga Yu. Spasskaya

11 Dm. Ulyanova street, 115478, Moscow

Scopus ID: 57226518518;

ospasskaa@gmail.com

https://orcid.org/0000-0003-2669-9457

Горбачева

А. М.

Gorbacheva

A. M.

Горбачева Анна Максимовна, к.м.н.

Москва

Researcher ID: HKO-2637-2023

Scopus Author ID: 57190977461

Anna M. Gorbacheva, MD, PhD

Researcher ID: HKO-2637-2023

Scopus Author ID: 57190977461

https://orcid.org/0000-0001-5952-5846

Бибик

Е. Е.

Bibik

E. E.

Бибик Екатерина Евгеньевна, к.м.н.

Москва

Researcher ID: AAY-3052-2020

Scopus Author ID: 57195679482

Ekaterina E. Bibik, MD, PhD

Researcher ID: AAY-3052-2020

Scopus Author ID: 57195679482

bibik.ekaterina@endocrincentr.ru

https://orcid.org/0000-0002-0532-9126

Тихонов

И. Н.

Tikhonov

I. N.

Тихонов Игорь Николаевич

Москва

Researcher ID: ABC-4408-2020

Scopus Author ID: 57200597669

Igor N. Tikhonov, MD

Researcher ID: ABC-4408-2020

Scopus Author ID: 57200597669

antihbs@gmail.com

https://orcid.org/0000-0001-6667-062X

Еремкина

А. К.

Eremkina

A. K.

Еремкина Анна Константиновна, к.м.н.

Москва

Researcher ID: R-8848-2019

Scopus Author ID: 57197775339

Anna K. Eremkina, MD, PhD

Researcher ID: R-8848-2019

Scopus Author ID: 57197775339

eremkina.anna@endocrincentr.ru

https://orcid.org/0000-0002-6758-5918

Хайриева

А. В.

Khairieva

A. V.

Хайриева Ангелина Владимировна

Москва

Angelina V. Khairieva, MD

komarito@mail.ru

https://orcid.org/0000-0003-4830-0152

Литвинова

Е. Е.

Litvinova

E. E.

Литвинова Елена Евгеньевна

Москва

litvinova.elena@endocrincentr.ru

https://orcid.org/0000-0002-9717-9742

Мокрышева

Н. Г.

Mokrysheva

N. G.

Мокрышева Наталья Георгиевна, д.м.н., профессор, академик РАН

Москва

ResearcherID: AAY-3761-2020

Scopus Author ID: 35269746000

Natalia G. Mokrysheva, MD, PhD, Professor, RAS Academician

ResearcherID: AAY-3761-2020

Scopus Author ID: 35269746000

mokrisheva.natalia@endocrincentr.ru

ФГБУ «НМИЦ эндокринологии им. академика И.И. Дедова» Минздрава РоссииРоссияEndocrinology Research CentreRussian Federation

ИКМ им. Н.В. Склифосовского Первого МГМУ имени И.М. СеченоваРоссияFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Russian Federation

2026

14022026

231

Спецвыпуск

4050

2026

Спасская О.Ю., Горбачева А.М., Бибик Е.Е., Тихонов И.Н., Еремкина А.К., Хайриева А.В., Литвинова Е.Е., Мокрышева Н.Г.

Spasskaya O.Y., Gorbacheva A.M., Bibik E.E., Tikhonov I.N., Eremkina A.K., Khairieva A.V., Litvinova E.E., Mokrysheva N.G.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.omet-endojournals.ru/jour/article/view/13290

Нарушения минерального обмена — одна из важнейших проблем здравоохранения в России и во всем мире. Патогенетически они могут обусловлены различной патологией, в том числе хроническими заболеваниями печени (ХЗП). Нарушения минерального обмена при ХЗП включают в себя печеночную остеодистрофию, остеопороз, дефицит витамина D, вторичный гиперпаратиреоз, гипокальциемию и др. Эти нарушения широко распространены в данной когорте больных, однако отсутствие единых комплексных клинических рекомендаций не позволяет своевременно выявлять данные осложнения ХЗП. В первой части обзора нами была рассмотрена эпидемиология и патофизиология нарушений минерального обмена при ХЗП, вторая часть посвящена вопросам их диагностики.

Disorders of mineral metabolism are one of the most significant healthcare challenges in Russia and worldwide. Pathogenetically, they can be caused by various pathologies, including chronic liver diseases (CLD). Mineral metabolism disorders in CLD include hepatic osteodystrophy, osteoporosis, vitamin D deficiency, secondary hyperparathyroidism, hypocalcemia, and others. These disorders are highly prevalent in this patient cohort; however, the lack of unified comprehensive clinical guidelines hinders the timely detection of these complications of CLD. In the first part of the review, we examined the epidemiology and pathophysiology of mineral metabolism disorders in CLD, while the second part focuses on their diagnosis.

хронические заболевания печеницирроз печенипеченочная остеодистрофияминеральные нарушенияостеопорозвитамин Dдиагностика

chronic liver diseasesliver cirrhosishepatic osteodystrophymineral disordersosteoporosisvitamin Dmanagement

Работа проведена в рамках гранта РНФ №24-25-00348 «Нарушения метаболизма витамина D и особенности костного ремоделирования у пациентов с циррозом печени различной этиологии»

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The authors declare that there are no conflicts of interest present.