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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet13143</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-13143</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group></article-categories><title-group><article-title>Опыт хирургического лечения морбидного ожирения у пациента с гиперкортицизмом и первичным гиперпаратиреозом: расстановка приоритетов</article-title><trans-title-group xml:lang="en"><trans-title>Experience of surgical treatment of morbid obesity in a patient with hypercortisolism and primary hyperparathyroidism: prioritization</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6624-2374</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комшилова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Komshilova</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Комшилова Ксения Андреевна, к.м.н.</p><p>117036, Москва, ул. Дм. Ульянова, д. 11</p></bio><bio xml:lang="en"><p>Kseniya A. Komshilova, PhD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p></bio><email xlink:type="simple">Komshilova.Kseniya@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7106-7753</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Череданова</surname><given-names>В. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Cheredanova</surname><given-names>V. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Череданова Виктория Романовна</p><p>117036, Москва, ул. Дм. Ульянова, д. 11</p></bio><bio xml:lang="en"><p>Vikroriia R. Cheredanova</p><p>11 Dm. Ulyanova street, 117036 Moscow</p></bio><email xlink:type="simple">vcheredanova@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6220-4397</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ершова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ershova</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ершова Екатерина Владимировна, к.м.н.</p><p>117036, Москва, ул. Дм. Ульянова, д. 11</p></bio><bio xml:lang="en"><p>Ekaterina V. Ershova, MD, PhD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p></bio><email xlink:type="simple">yu99pol06@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8077-9381</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазурина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazurina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазурина Наталия Валентиновна, д.м.н.</p><p>117036, Москва, ул. Дм. Ульянова, д. 11 </p><p>Researcher ID: S-2312-2016</p></bio><bio xml:lang="en"><p>Natalya V. Mazurina, MD, PhD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p><p>Researcher ID: S-2312-2016</p></bio><email xlink:type="simple">natalyamazurina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6388-1544</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платонова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Platonova</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Платонова Надежда Михайловна, д.м.н. </p><p>117036, Москва, ул. Дм. Ульянова, д. 11 </p></bio><bio xml:lang="en"><p>Nadezhda M. Platonova, MD, PhD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p></bio><email xlink:type="simple">doc-platonova@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7098-4584</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бельцевич</surname><given-names>Д. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Beltsevich</surname><given-names>D. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бельцевич Дмитрий Германович, д.м.н.</p><p>117036, Москва, ул. Дм. Ульянова, д. 11 </p></bio><bio xml:lang="en"><p>Dmitry G. Beltsevich, MD, PhD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p></bio><email xlink:type="simple">Belcevich.Dmitry@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8771-8300</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юкина</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Yukina</surname><given-names>M. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юкина Марина Юрьевна, к.м.н.</p><p>117036, Москва, ул. Дм. Ульянова, д. 11 </p></bio><bio xml:lang="en"><p>Marina Yu. Yukina, MD, PhD</p><p>11 Dm. Ulyanova street, 117036 Moscow</p></bio><email xlink:type="simple">kuronova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8520-8702</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трошина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Troshina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трошина Екатерина Анатольевна, д.м.н., профессор, член-корреспондент РАН</p><p>117036, Москва, ул. Дм. Ульянова, д. 11 </p></bio><bio xml:lang="en"><p>Ekaterina A. Troshina, MD, PhD, professor</p><p>11 Dm. Ulyanova street, 117036 Moscow</p></bio><email xlink:type="simple">troshina@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГНЦ РФ ФГБУ «Национальный медицинский исследовательский центр эндокринологии» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>08</day><month>10</month><year>2024</year></pub-date><volume>21</volume><issue>4</issue><fpage>405</fpage><lpage>411</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Комшилова К.А., Череданова В.Р., Ершова Е.В., Мазурина Н.В., Платонова Н.В., Бельцевич Д.Г., Юкина М.Ю., Трошина Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Комшилова К.А., Череданова В.Р., Ершова Е.В., Мазурина Н.В., Платонова Н.В., Бельцевич Д.Г., Юкина М.Ю., Трошина Е.А.</copyright-holder><copyright-holder xml:lang="en">Komshilova K.A., Cheredanova V.R., Ershova E.V., Mazurina N.V., Platonova N.M., Beltsevich D.G., Yukina M.Y., Troshina E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/13143">https://www.omet-endojournals.ru/jour/article/view/13143</self-uri><abstract><p>Морбидное ожирение представляет собой патологию, ассоциированную с комплексом метаболических нарушений, сахарным диабетом 2 типа, сердечно-сосудистыми заболеваниями, ведущими к крайне негативным последствиям для здоровья, что обусловливает необходимость мультидисциплинарного подхода. Приводимый клинический случай является примером сочетания первичного (экзогенно-конституционального) ожирения с двумя другими эндокринными заболеваниями и демонстрирует важность определения оптимальной тактики лечения пациента с морбидным ожирением с учетом его сопутствующих заболеваний. Поэтапное лечение пациента проводилось командой специалистов терапевтического и хирургического профилей</p></abstract><trans-abstract xml:lang="en"><p>Morbid obesity is a pathology associated with a complex of metabolic disorders, type 2 diabetes mellitus, and cardiovascular diseases, leading to extremely negative health consequences, which necessitates a multidisciplinary approach. The presented clinical case is an example of a combination of primary (exogenous-constitutional) obesity with two other endocrine diseases, and it demonstrates the importance of determining the optimal treatment tactic for a patient with morbid obesity, taking into account his concomitant diseases. Step-by-step patient treatment was carried out by a team of therapeutic and surgical specialists</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>бариатрическая операция</kwd><kwd>первичный гиперпаратиреоз</kwd><kwd>сахарный диабет</kwd><kwd>гиперплазия надпочечников</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>bariatric surgery</kwd><kwd>primary hyperparathyroidism</kwd><kwd>diabetes mellitus</kwd><kwd>adrenal hyperplasia</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Публикация подготовлена в рамках государственного задания «Механизмы дезадаптации двухуровневой системы регуляции аппетита при экзогенно-конституциональном ожирении с множественными осложнениями и способы ее коррекции» Рег. № НИОКТР 122012100180-0.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ammori BJ, MC Skarulis, H Soran, et al. 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