ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/omet13092ometendo-13092Research ArticleОБЗОРЫREVIEWSПерспективы применения полифенолов у пациентов с бронхиальной астмой на фоне ожиренияProspects for the use of polyphenols in patients with bronchial asthma and obesityhttps://orcid.org/0000-0001-9640-754XБелоглазовВ. А.BeloglazovV. A.

 Белоглазов Владимир Алексеевич, д.м.н., профессор, кафедра внутренней медицины №2

295051, Симферополь, бульвар Ленина, д. 5/7

Scopus Author ID: 7007129056

Vladimir A. Beloglazov, MD, PhD, Professor, Department of Internal Medicine №2

5/7 Lenin Boulevard street, 295051 Simferopol

biloglazov@mail.ruhttps://orcid.org/0000-0002-5486-7262ЯцковИ. А.YatskovI. A.

Яцков Игорь Анатольевич, к.м.н., кафедра внутренней медицины №2

295051, Симферополь, бульвар Ленина, д. 5/7

Scopus Author ID: 57218873902

Igor A. Yatskov, PhD, Department of Internal Medicine №2

5/7 Lenin Boulevard street, 295051 Simferopol

egermd@yandex.ruhttps://orcid.org/0009-0001-9549-5477МоикА. А.MoikA. A.

Моик Анастасия Андреевна, кафедра внутренней медицины №2

295051, Симферополь, бульвар Ленина, д. 5/7

Anastasia A. Moik, Department of Internal Medicine №2

5/7 Lenin Boulevard street, 295051 Simferopol

asyabublik2000@mail.ruhttps://orcid.org/0009-0005-2467-8435МоикА. В.MoikAndrey Vladimirovich

Моик Андрей Владимирович, кафедра внутренней медицины №2

295051, Симферополь, бульвар Ленина, д. 5/7

Andrey V. Moik, Department of Internal Medicine №2

5/7 Lenin Boulevard street, 295051 Simferopol

dartbatman5@gmail.com«Ордена Трудового Красного Знамени медицинский институт им. С.И. Георгиевского»; ФГАОУ ВО «Крымский федеральный университет имени В.И. Вернадского»РоссияOrder of the Red Banner of Labor S.I. Georgievsky Medical Institute V.I. Vernadsky Crimean Federal UniversityRussian Federation«Ордена Трудового Красного Знамени медицинский институт им. С.И. Георгиевского»; ФГАОУ ВО «Крымский федеральный университет имени В.И. Вернадского»РоссияOrder of the Red Banner of Labor S. I. Georgievsky Medical Institute V. I. Vernadsky Crimean Federal UniversityRussian Federation202417062024214357364Copyright © Белоглазов В.А., Яцков И.А., Моик А.А., Моик А.В., 20252025Белоглазов В.А., Яцков И.А., Моик А.А., Моик А.В.Beloglazov V.A., Yatskov I.A., Moik A.A., Moik A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/13092

Бронхиальная астма (БА) и ожирение представляют собой заболевания, характеризующиеся вариабельностью течения и возможных осложнений, частота встречаемости которых растет из года в год. Взаимосвязь ожирения и БА до сих пор остается актуальной проблемой системы здравоохранения. Представляя собой весьма распространенные заболевания, они утяжеляют течение друг друга и значительно ухудшают качество жизни. Полифенолы — подающий надежды вариант для решения имеющейся проблемы. Данные низкомолекулярные соединения представляют собой биологически активные вещества, способные воздействовать на многие метаболические процессы в организме. В представленном обзоре продемонстрированы множественные свойства этих уникальных микронутриентов, в том числе антиоксидантные, антиканцерогенные, противовоспалительные, метаболические, нейропротективные и многие другие. Внедрение полифенолов в ежедневный рацион может поспособствовать укреплению общественного здоровья, снижению частоты и прогрессирования социально-значимых заболеваний, а применяя данные соединения при таких заболеваниях, как бронхиальная астма и ожирение, согласно многочисленным современным исследованиям, и вовсе удается добиться выраженного терапевтического эффекта. Цель данного литературного обзора — проследить связь между эффектом применения полифенолов и изменением течения заболевания и качества жизни у пациентов с бронхиальной астмой на фоне ожирения, опираясь на данные современных источников

Asthma and obesity are diseases characterized by variability in the course and possible complications, the frequency of which is steadily increasing from year to year. The correlation between obesity and asthma is still an acute problem of the health care system. Representing very common diseases, they aggravate each other’s course and significantly worsen the quality of life. Polyphenols are a promising option to solve the existing problem. These low molecular weight compounds are biologically active substances capable of influencing on many metabolic processes in the body. This review demonstrates the multiple properties of these unique micronutrients, including antioxidant, anti-carcinogenic, anti-inflammatory, metabolic, neuroprotective and many others. The integration of polyphenols into the daily diet can contribute to strengthening public health, reducing the frequency and progression of socially significant diseases, and using these compounds in diseases such as asthma and obesity, according to numerous modern studies, it is possible to achieve a significant therapeutic effect at all. The purpose of this literature review is to trace the correlation between the effect of using polyphenols and changes in the course of the disease and quality of life in patients with asthma on the background of obesity, based on facts from advanced sources.

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The authors declare that there are no conflicts of interest present.