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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet12714</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-12714</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL PRACTICE GUIDELINES</subject></subj-group></article-categories><title-group><article-title>МЕЖДИСЦИПЛИНАРНЫЕ КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ «ЛЕЧЕНИЕ ОЖИРЕНИЯ И КОМОРБИДНЫХ ЗАБОЛЕВАНИЙ»</article-title><trans-title-group xml:lang="en"><trans-title>INTERDISCIPLINARY CLINICAL PRACTICE GUIDELINES "MANAGEMENT OF OBESITY AND ITS COMORBIDITIES"</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8175-7886</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дедов</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Dedov</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН</p><p>ResearcherID: D-3729-2014; Scopus Author ID: 7101843976; eLibrary SPIN: 5873-2280 Москва </p></bio><bio xml:lang="en"><p>MD, PhD, Professor, academician of RAS</p><p>ResearcherID: D-3729-2014; Scopus Author ID: 7101843976; </p><p>eLibrary SPIN: 5873-2280 Moscow</p></bio><email xlink:type="simple">dedov@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3893-9972</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестакова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН </p><p>eLibrary SPIN: 7584-7015 Москва </p></bio><bio xml:lang="en"><p>MD, PhD, Professor, academician of RAS</p><p>eLibrary SPIN: 7584-7015 Moscow</p></bio><email xlink:type="simple">nephro@endocrincentr.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5634-7877</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельниченко</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnichenko</surname><given-names>G. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, академик РАН </p><p>eLibrary SPIN: 8615-0038Москва </p></bio><bio xml:lang="en"><p>MD, PhD, Professor, academician of RAS</p><p>eLibrary SPIN: 8615-0038 Moscow</p></bio><email xlink:type="simple">teofrast2000@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8077-9381</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазурина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazurina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.Москва </p></bio><bio xml:lang="en"><p>MD, PhD</p><p>eLibrary SPIN: 9067-3062 Moscow</p></bio><email xlink:type="simple">natalyamazurina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8425-0020</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреева</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreeva</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p><p>eLibrary SPIN: 1239-2937 Москва </p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p><p>eLibrary SPIN: 1239-2937 Moscow</p></bio><email xlink:type="simple">endogin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5178-6029</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бондаренко</surname><given-names>И. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Bondarenko</surname><given-names>I. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н</p><p>eLibrary SPIN: 4524-4803 Москва </p></bio><bio xml:lang="en"><p>MD, PhD</p><p>eLibrary SPIN: 4524-4803 Moscow</p></bio><email xlink:type="simple">iz_bondarenko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2516-2570</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусова</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Gusova</surname><given-names>Z. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p><p>eLibrary SPIN: 7295-5053</p><p>Ростов-на-Дону</p></bio><bio xml:lang="en"><p>MD, PhD</p><p>eLibrary SPIN: 7295-5053 </p><p>Rostov-on-Don </p></bio><email xlink:type="simple">docgzr@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0327-4619</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дзгоева</surname><given-names>Ф. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzgoeva</surname><given-names>F. 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V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p><p>eLibrary SPIN: 6728-3764 Москва </p></bio><bio xml:lang="en"><p>MD, PhD</p><p>eLibrary SPIN: 6728-3764 Moscow</p></bio><email xlink:type="simple">yu99pol06@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9198-8661</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавлева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravleva</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p><p>eLibrary SPIN: 6267-9901</p><p>Москва</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p><p>eLibrary SPIN: 6267-9901 Moscow</p></bio><email xlink:type="simple">mvzhuravleva@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарчук</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharchuk</surname><given-names>T. 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N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>eLibrary SPIN: 6237-1310 Москва </p></bio><bio xml:lang="en"><p>MD</p><p>eLibrary SPIN: 6237-1310 Moscow</p></bio><email xlink:type="simple">pilipenkowork@rambler.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3525-9891</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сметанина</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Smetanina</surname><given-names>S. 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V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н. </p><p>eLibrary SPIN: 9413-5136 Москва </p></bio><bio xml:lang="en"><p>MD, PhD</p><p>eLibrary SPIN: 9413-5136 </p><p>Moscow</p></bio><email xlink:type="simple">s1981k@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр эндокринологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Endocrinology Research Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Ростовский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Rostov State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский институт ревматологии имени В.А. 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Yevdokimov Moscow State University of Medicine and Dentistry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian National Research Medical University named after N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru"><institution>Новосибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-12"><aff xml:lang="ru"><institution>Тюменский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Tyumen State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-13"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет имени Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian National Research Medical University named after N.I. Pirogov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-14"><aff xml:lang="ru"><institution>Российский университет дружбы народов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Peoples’ Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-15"><aff xml:lang="ru"><institution>Московский городской педагогический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow City University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>11</day><month>02</month><year>2021</year></pub-date><volume>18</volume><issue>1</issue><fpage>5</fpage><lpage>99</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дедов И.И., Шестакова М.В., Мельниченко Г.А., Мазурина Н.В., Андреева Е.Н., Бондаренко И.З., Гусова З.Р., Дзгоева Ф.Х., Елисеев М.С., Ершова Е.В., Журавлева М.В., Захарчук Т.А., Исаков В.А., Клепикова М.В., Комшилова К.А., Крысанова В.С., Недогода С.В., Новикова А.М., Остроумова О.Д., Переверзев А.П., Роживанов Р.В., Романцова Т.И., Руяткина Л.А., Саласюк А.С., Сасунова А.Н., Сметанина С.А., Стародубова А.В., Суплотова Л.А., Ткачева О.Н., Трошина Е.А., Хамошина М.Б., Чечельницкая С.М., Шестакова Е.А., Шереметьева Е.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Дедов И.И., Шестакова М.В., Мельниченко Г.А., Мазурина Н.В., Андреева Е.Н., Бондаренко И.З., Гусова З.Р., Дзгоева Ф.Х., Елисеев М.С., Ершова Е.В., Журавлева М.В., Захарчук Т.А., Исаков В.А., Клепикова М.В., Комшилова К.А., Крысанова В.С., Недогода С.В., Новикова А.М., Остроумова О.Д., Переверзев А.П., Роживанов Р.В., Романцова Т.И., Руяткина Л.А., Саласюк А.С., Сасунова А.Н., Сметанина С.А., Стародубова А.В., Суплотова Л.А., Ткачева О.Н., Трошина Е.А., Хамошина М.Б., Чечельницкая С.М., Шестакова Е.А., Шереметьева Е.В.</copyright-holder><copyright-holder xml:lang="en">Dedov I.I., Shestakova M.V., Melnichenko G.A., Mazurina N.V., Andreeva E.N., Bondarenko I.Z., Gusova Z.R., Dzgoeva F.K., Eliseev M.S., Ershova E.V., Zhuravleva M.V., Zakharchuk T.A., Isakov V.A., Klepikova M.V., Komshilova K.A., Krysanova V.S., Nedogoda S.V., Novikova A.M., Ostroumova O.D., Pereverzev A.P., Rozhivanov R.V., Romantsova T.I., Ruyatkina L.A., Salasyuk A.S., Sasunova A.N., Smetanina S.A., Starodubova A.V., Suplotova L.A., Tkacheva O.N., Troshina E.A., Khamoshina M.V., Chechelnitskaya S.M., Shestakova E.A., Sheremet’eva E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/12714">https://www.omet-endojournals.ru/jour/article/view/12714</self-uri><abstract><p>Клинические рекомендации уже давно вошли в число рабочих инструментов современного врача, помогая  ему быстро ориентироваться в наиболее эффективных доказанных методах лечения и профилактики  различных заболеваний, а также адаптировать эти методы к конкретным задачам своих больных и  добиваться максимальной персонализации лечения. Клинические рекомендации составляются  профессиональными некоммерческими ассоциациями и одобряются научным советом МЗ РФ, при этом  нередко одна рекомендация готовится двумя или даже тремя ассоциациями. Особенность предлагаемых  вашему вниманию рекомендаций в том, что в профилактику и лечение ожирения вовлекаются не только  эндокринологи, но и терапевты, кардиологи, гинекологи, гастроэнтерологи и врачи многих других  специальностей. Мультидисциплинарная рабочая группа представляет этот проект в многопрофильном журнале с целью объединения усилий нескольких профессиональных ассоциаций, что связано с необходимостью уделить внимание не только самому ожирению, но и коморбидным состояниям. Мы надеемся на конструктивную критику и разностороннее обсуждение проблемы на страницах нашего журнала.</p></abstract><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>клинические рекомендации</kwd><kwd>артериальная гипертензия</kwd><kwd>бандажирование желудка</kwd><kwd>бариатрическая / метаболическая хирургия</kwd><kwd>билиопанкреатическое шунтирование</kwd><kwd>гипокалорийное питание</kwd><kwd>желудочное шунтирование</kwd><kwd>лираглутид</kwd><kwd>морбидное ожирение</kwd><kwd>ожирение</kwd><kwd>орлистат</kwd><kwd>рукавная гастрэктомия</kwd><kwd>сахарный диабет 2 типа</kwd><kwd>сибутрамин</kwd><kwd>обструктивное апноэ сна</kwd><kwd>физическая активность</kwd><kwd>постменопауза</kwd><kwd>неалкогольная жировая болезнь печени</kwd><kwd>гиперурикемия</kwd><kwd>подагра</kwd></kwd-group><kwd-group xml:lang="en"><kwd>guidelines</kwd><kwd>arterial hypertension</kwd><kwd>gastric banding</kwd><kwd>bariatric / metabolic surgery</kwd><kwd>biliopancreatic diversion (BPD)</kwd><kwd>hypocaloric nutrition</kwd><kwd>gastric bypass</kwd><kwd>liraglutide</kwd><kwd>morbid obesity</kwd><kwd>obesity</kwd><kwd>orlistat</kwd><kwd>sleeve gastrectomy</kwd><kwd>type 2 diabetes</kwd><kwd>sibutramin</kwd><kwd>obstructive sleep apnoe</kwd><kwd>physical activity</kwd><kwd>postmenopause</kwd><kwd>non-alcoholic fatty liver disease</kwd><kwd>hyperuricemia</kwd><kwd>gout</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Must A. 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