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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ometendo</journal-id><journal-title-group><journal-title xml:lang="ru">Ожирение и метаболизм</journal-title><trans-title-group xml:lang="en"><trans-title>Obesity and metabolism</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2071-8713</issn><issn pub-type="epub">2306-5524</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/omet10090</article-id><article-id custom-type="elpub" pub-id-type="custom">ometendo-10090</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзор литературы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Нерешенные вопросы витаминно-минеральной поддержки пациентов, перенесших бариатрические операции</article-title><trans-title-group xml:lang="en"><trans-title>Unsolved issues related to multivitamin and multimineral support for patients following bariatric surgery</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2968-4891</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малыхина</surname><given-names>Александра Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Malykhina</surname><given-names>Aleksandra I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">sandroka@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6592-1036</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яшков</surname><given-names>Юрий Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Yashkov</surname><given-names>Yuriy I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">yu@yashkov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8979-8084</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимов</surname><given-names>Максим Леонидович</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimov</surname><given-names>Maksim L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><email xlink:type="simple">maksim_maksimov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Многопрофильная клиника АО «Центр эндохирургии и литотрипсии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center of Endosurgery and Lithotripsy.</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>25</day><month>12</month><year>2019</year></pub-date><volume>16</volume><issue>4</issue><fpage>31</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Малыхина А.И., Яшков Ю.И., Максимов М.Л., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Малыхина А.И., Яшков Ю.И., Максимов М.Л.</copyright-holder><copyright-holder xml:lang="en">Malykhina A.I., Yashkov Y.I., Maksimov M.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.omet-endojournals.ru/jour/article/view/10090">https://www.omet-endojournals.ru/jour/article/view/10090</self-uri><abstract><p>В обзорной статье рассматриваются нерешенные вопросы, касающиеся витаминно-минеральной поддержки пациентов, перенесших бариатрические операции.</p><p>У многих бариатрических пациентов еще до операции выявляются дефициты витаминов и микроэлементов, в связи с чем целесообразно проводить коррекцию выявленных нарушений витаминно-минерального статуса на этапе предоперационной подготовки.</p><p>Назначение витаминно-минеральных комплексов показано после любой бариатрической операции, но в зависимости от вида вмешательства состав и дозировка витаминов, макро- и микроэлементов должны различаться. Учитывая более выраженную гипоабсорбцию жиров и возможное развитие стеатореи после билиопанкреатического шунтирования (БПШ), требуются большие дозы жирорастворимых витаминов.</p><p>Имеющиеся на отечественном фармацевтическом рынке витаминно-минеральные комплексы не содержат необходимой дозировки железа, кальция, жирорастворимых витаминов, в связи с чем требуется дополнительное назначение этих и других макро- и микроэлементов (цинк, медь и др.). В то же время для обеспечения суточной потребности в витаминах, макро- и микроэлементах пациентам приходится одновременно принимать большое количество препаратов (до 10 таблеток или капсул в день), что приводит к нарушению комплаенса, а также к частичному или полному отказу от приема препаратов и к неизбежному росту послеоперационных осложнений, обусловленных метаболическими нарушениями.</p><p>Таким образом, обоснована целесообразность разработки серии отечественных витаминно-минеральных комплексов с высокой биодоступностью, которые содержали бы все необходимые компоненты и удовлетворяли суточные потребности в витаминах и микроэлементах у пациентов в зависимости от вида перенесенной операции.</p><p>Назначение данных препаратов позволит снизить частоту отдаленных метаболических нарушений за счет повышения комплаенса, удобства приема лекарственной формы препарата и сократить расходы на их приобретение</p></abstract><trans-abstract xml:lang="en"><p>In the review article the authors discuss unsolved issues regarding vitamin and mineral support of patients undergoing bariatric/metabolic operations. Many patients refer for the surgery already having deficiencies of macro- and micronutrients and need preoperative preparation for improving of vitamin-mineral status. Vitamin-mineral support is indicated after each bariatric operation, however the volume of nutritive support and the choice and doses of vitamins and minerals can be varied depending on type of surgery. Hypoabsorptive procedures such as duodenal switch or SADI-S (Single anastomosis duodeno–ileal bypass with sleeve gastrectomy) usually demand more significant protein, calcium and iron supplementations together with administration of multivitamin complexes containing fat-soluble vitamins. Existing standard vitamin-mineral complexes may not contain necessary doses of iron, calcium, fat-soluble and other vitamins as well as some microelements like cooper, zink, selenium etc. Thus, sufficient vitamin-mineral support may need up to 10 tablets or pills daily depending on kind of surgery. That can influence on patient’s compliance, lead to refusal of supplementations and thus to undesirable metabolic consequences after surgery. The authors have concluded about necessity of working out of cost-effective domestic series of vitamin-mineral combinations with high bio-availability specially adapted to every class of bariatric/metabolic operation. To author’s opinion this can lead to better patient’s compliance and can prevent undesirable side effects after metabolic surgery.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бариатрические операции</kwd><kwd>рестриктивные операции</kwd><kwd>гастрошунтирование</kwd><kwd>билиопанкреатическое шунтирование</kwd><kwd>витаминно-минеральные комплексы</kwd><kwd>витаминно-минеральная поддержка</kwd><kwd>дефициты витаминов и микроэлементов</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bariatric surgery</kwd><kwd>restrictive procedures</kwd><kwd>Roux-en-Y gastric bypass</kwd><kwd>biliopancreatic diversion</kwd><kwd>vitamin-mineral complexes</kwd><kwd>vitamin-mineral support</kwd><kwd>vitamin and mineral deficiences</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">who.int [Internet]. всемирная организация здравоохранения. центр сми. информационный бюллетень «ожирение и избыточный вес». [updated 2018 Feb 16; cited 2019 Dec 10]. Available from: https://www.who.int/ru/news-room/fact-sheets/detail/obesity-and-overweight</mixed-citation><mixed-citation xml:lang="en">who.int [Internet]. всемирная организация здравоохранения. центр сми. информационный бюллетень «ожирение и избыточный вес». [updated 2018 Feb 16; cited 2019 Dec 10]. Available from: https://www.who.int/ru/news-room/fact-sheets/detail/obesity-and-overweight</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Муромцева Г.А., Концевая А.В., Константинов В.В., и др. Распространенность факторов риска неинфекционных заболеваний в российской популяции в 2012–2013 гг. Результаты исследования ЭССЕ-РФ. // Кардиоваскулярная терапия и профилактика. — 2014. — Т. 13. — №6. — С. 4-11. [Muromtseva GA, Kontsevaya AV, Konstantinov VV, et al. The prevalence of non-infectious diseases risk factors in Russian population in 2012-2013 years. The results of ECVD-RF. Cardiovascular Therapy and Prevention. 2014;13(6):4-11. (In Russ).] DOI:10.15829/1728-8800-2014-6-4-11</mixed-citation><mixed-citation xml:lang="en">Муромцева Г.А., Концевая А.В., Константинов В.В., и др. Распространенность факторов риска неинфекционных заболеваний в российской популяции в 2012–2013 гг. Результаты исследования ЭССЕ-РФ. // Кардиоваскулярная терапия и профилактика. — 2014. — Т. 13. — №6. — С. 4-11. [Muromtseva GA, Kontsevaya AV, Konstantinov VV, et al. The prevalence of non-infectious diseases risk factors in Russian population in 2012-2013 years. The results of ECVD-RF. Cardiovascular Therapy and Prevention. 2014;13(6):4-11. (In Russ).] DOI:10.15829/1728-8800-2014-6-4-11</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med. 2003;348(17):1625-1638. DOI:10.1056/NEJMoa021423</mixed-citation><mixed-citation xml:lang="en">Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med. 2003;348(17):1625-1638. DOI:10.1056/NEJMoa021423</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">National Heart, Lung and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. 1998.</mixed-citation><mixed-citation xml:lang="en">National Heart, Lung and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report. 1998.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Guh DP, Zhang W, Bansback N, et al. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009;9:88. DOI:10.1186/1471-2458-9-88</mixed-citation><mixed-citation xml:lang="en">Guh DP, Zhang W, Bansback N, et al. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis. BMC Public Health. 2009;9:88. DOI:10.1186/1471-2458-9-88</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Mechanick JI, Youdim A, Jones DB, et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic &amp; Bariatric Surgery. Obesity (Silver Spring). 2013;21 Suppl 1:S1-27. DOI:10.1002/oby.20461</mixed-citation><mixed-citation xml:lang="en">Mechanick JI, Youdim A, Jones DB, et al. Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient--2013 update: cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic &amp; Bariatric Surgery. Obesity (Silver Spring). 2013;21 Suppl 1:S1-27. DOI:10.1002/oby.20461</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Бодунова Н.А. Влияние бариатрических операций на содержание витаминов у больных с ожирением: Автореф. дис. … канд. мед. наук. — М.; 2016. [Bodunova NA. Vliyanie bariatricheskikh operatsiy na soderzhanie vitaminov u bol’nykh s ozhireniem. [dissertation] Moscow; 2016. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Бодунова Н.А. Влияние бариатрических операций на содержание витаминов у больных с ожирением: Автореф. дис. … канд. мед. наук. — М.; 2016. [Bodunova NA. Vliyanie bariatricheskikh operatsiy na soderzhanie vitaminov u bol’nykh s ozhireniem. [dissertation] Moscow; 2016. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Maggard MA, Shugarman LR, Suttorp M, et al. Meta-analysis: surgical treatment of obesity. Ann Intern Med. 2005;142(7):547-559. DOI:10.7326/0003-4819-142-7-200504050-00013</mixed-citation><mixed-citation xml:lang="en">Maggard MA, Shugarman LR, Suttorp M, et al. Meta-analysis: surgical treatment of obesity. Ann Intern Med. 2005;142(7):547-559. DOI:10.7326/0003-4819-142-7-200504050-00013</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mattar SG, Velcu LM, Rabinovitz M, et al. Surgically-induced weight loss significantly improves nonalcoholic fatty liver disease and the metabolic syndrome. Ann Surg. 2005;242(4):610-617; discussion 618-620. DOI:10.1097/01.sla.0000179652.07502.3f</mixed-citation><mixed-citation xml:lang="en">Mattar SG, Velcu LM, Rabinovitz M, et al. Surgically-induced weight loss significantly improves nonalcoholic fatty liver disease and the metabolic syndrome. Ann Surg. 2005;242(4):610-617; discussion 618-620. DOI:10.1097/01.sla.0000179652.07502.3f</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Karlsson J, Taft C, Ryden A, et al. Ten-year trends in health-related quality of life after surgical and conventional treatment for severe obesity: the SOS intervention study. Int J Obes (Lond). 2007;31(8):1248-1261. DOI:10.1038/sj.ijo.0803573</mixed-citation><mixed-citation xml:lang="en">Karlsson J, Taft C, Ryden A, et al. Ten-year trends in health-related quality of life after surgical and conventional treatment for severe obesity: the SOS intervention study. Int J Obes (Lond). 2007;31(8):1248-1261. DOI:10.1038/sj.ijo.0803573</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Sjostrom L, Lindroos AK, Peltonen M, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683-2693. DOI:10.1056/NEJMoa035622</mixed-citation><mixed-citation xml:lang="en">Sjostrom L, Lindroos AK, Peltonen M, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683-2693. DOI:10.1056/NEJMoa035622</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Sjostrom L. Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219-234. DOI:10.1111/joim.12012</mixed-citation><mixed-citation xml:lang="en">Sjostrom L. Review of the key results from the Swedish Obese Subjects (SOS) trial - a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273(3):219-234. DOI:10.1111/joim.12012</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Yumuk V, Tsigos C, Fried M, et al. European Guidelines for Obesity Management in Adults. Obes Facts. 2015;8(6):402-424. DOI:10.1159/000442721</mixed-citation><mixed-citation xml:lang="en">Yumuk V, Tsigos C, Fried M, et al. European Guidelines for Obesity Management in Adults. Obes Facts. 2015;8(6):402-424. DOI:10.1159/000442721</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Angrisani L, Santonicola A, Iovino P, et al. Bariatric Surgery Worldwide 2013. Obes Surg. 2015;25(10):1822-1832. DOI:10.1007/s11695-015-1657-z</mixed-citation><mixed-citation xml:lang="en">Angrisani L, Santonicola A, Iovino P, et al. Bariatric Surgery Worldwide 2013. Obes Surg. 2015;25(10):1822-1832. DOI:10.1007/s11695-015-1657-z</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Российское общество хирургов, общество бариатрических хирургов. Клинические рекомендации по бариатрической и метаболической терапии. — М.; 2014. [Rossiyskoe obshchestvo khirurgov, obshchestvo bariatricheskikh khirurgov. Klinicheskie rekomendatsii po bariatricheskoy i metabolicheskoy terapii. Moscow; 2014. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Российское общество хирургов, общество бариатрических хирургов. Клинические рекомендации по бариатрической и метаболической терапии. — М.; 2014. [Rossiyskoe obshchestvo khirurgov, obshchestvo bariatricheskikh khirurgov. Klinicheskie rekomendatsii po bariatricheskoy i metabolicheskoy terapii. Moscow; 2014. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kimmons JE, Blanck HM, Tohill BC, et al. Associations between body mass index and the prevalence of low micronutrient levels among US adults. MedGenMed. 2006;8(4):59.</mixed-citation><mixed-citation xml:lang="en">Kimmons JE, Blanck HM, Tohill BC, et al. Associations between body mass index and the prevalence of low micronutrient levels among US adults. MedGenMed. 2006;8(4):59.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Wortsman J, Matsuoka LY, Chen TC, et al. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3):690-693. DOI:10.1093/ajcn/72.3.690</mixed-citation><mixed-citation xml:lang="en">Wortsman J, Matsuoka LY, Chen TC, et al. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3):690-693. DOI:10.1093/ajcn/72.3.690</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Cepeda-Lopez AC, Aeberli I, Zimmermann MB. Does obesity increase risk for iron deficiency? A review of the literature and the potential mechanisms. Int J Vitam Nutr Res. 2010;80(4-5):263-270. DOI:10.1024/0300-9831/a000033</mixed-citation><mixed-citation xml:lang="en">Cepeda-Lopez AC, Aeberli I, Zimmermann MB. Does obesity increase risk for iron deficiency? A review of the literature and the potential mechanisms. Int J Vitam Nutr Res. 2010;80(4-5):263-270. DOI:10.1024/0300-9831/a000033</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Marreiro DN, Fisberg M, Cozzolino SM. Zinc nutritional status and its relationships with hyperinsulinemia in obese children and adolescents. Biol Trace Elem Res. 2004;100(2):137-149. DOI:10.1385/bter:100:2:137</mixed-citation><mixed-citation xml:lang="en">Marreiro DN, Fisberg M, Cozzolino SM. Zinc nutritional status and its relationships with hyperinsulinemia in obese children and adolescents. Biol Trace Elem Res. 2004;100(2):137-149. DOI:10.1385/bter:100:2:137</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Toh SY, Zarshenas N, Jorgensen J. Prevalence of nutrient deficiencies in bariatric patients. Nutrition. 2009;25(11-12):1150-1156. DOI:10.1016/j.nut.2009.03.012</mixed-citation><mixed-citation xml:lang="en">Toh SY, Zarshenas N, Jorgensen J. Prevalence of nutrient deficiencies in bariatric patients. Nutrition. 2009;25(11-12):1150-1156. DOI:10.1016/j.nut.2009.03.012</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Bavaresco M, Paganini S, Lima TP, et al. Nutritional course of patients submitted to bariatric surgery. Obes Surg. 2010;20(6):716-721. DOI:10.1007/s11695-008-9721-6</mixed-citation><mixed-citation xml:lang="en">Bavaresco M, Paganini S, Lima TP, et al. Nutritional course of patients submitted to bariatric surgery. Obes Surg. 2010;20(6):716-721. DOI:10.1007/s11695-008-9721-6</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Flancbaum L, Belsley S, Drake V, et al. Pre-operative nutritional status of patients undergoing Roux-en-Y gastric bypass for morbid obesity. J Gastrointest Surg. 2006;10(7):1033-1037. DOI:10.1016/j.gassur.2006.03.004</mixed-citation><mixed-citation xml:lang="en">Flancbaum L, Belsley S, Drake V, et al. Pre-operative nutritional status of patients undergoing Roux-en-Y gastric bypass for morbid obesity. J Gastrointest Surg. 2006;10(7):1033-1037. DOI:10.1016/j.gassur.2006.03.004</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Allied Health Sciences Section Ad Hoc Nutrition C, Aills L, Blankenship J, et al. ASMBS Allied Health Nutritional Guidelines for the Surgical Weight Loss Patient. Surg Obes Relat Dis. 2008;4(5 Suppl):S73-108. DOI:10.1016/j.soard.2008.03.002</mixed-citation><mixed-citation xml:lang="en">Allied Health Sciences Section Ad Hoc Nutrition C, Aills L, Blankenship J, et al. ASMBS Allied Health Nutritional Guidelines for the Surgical Weight Loss Patient. Surg Obes Relat Dis. 2008;4(5 Suppl):S73-108. DOI:10.1016/j.soard.2008.03.002</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Xanthakos SA. Nutritional deficiencies in obesity and after bariatric surgery. Pediatr Clin North Am. 2009;56(5):1105-1121. DOI:10.1016/j.pcl.2009.07.002</mixed-citation><mixed-citation xml:lang="en">Xanthakos SA. Nutritional deficiencies in obesity and after bariatric surgery. Pediatr Clin North Am. 2009;56(5):1105-1121. DOI:10.1016/j.pcl.2009.07.002</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Aasheim ET, Hofso D, Hjelmesaeth J, et al. Vitamin status in morbidly obese patients: a cross-sectional study. Am J Clin Nutr. 2008;87(2):362-369. DOI:10.1093/ajcn/87.2.362</mixed-citation><mixed-citation xml:lang="en">Aasheim ET, Hofso D, Hjelmesaeth J, et al. Vitamin status in morbidly obese patients: a cross-sectional study. Am J Clin Nutr. 2008;87(2):362-369. DOI:10.1093/ajcn/87.2.362</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Ernst B, Thurnheer M, Schmid SM, Schultes B. Evidence for the necessity to systematically assess micronutrient status prior to bariatric surgery. Obes Surg. 2009;19(1):66-73. DOI:10.1007/s11695-008-9545-4</mixed-citation><mixed-citation xml:lang="en">Ernst B, Thurnheer M, Schmid SM, Schultes B. Evidence for the necessity to systematically assess micronutrient status prior to bariatric surgery. Obes Surg. 2009;19(1):66-73. DOI:10.1007/s11695-008-9545-4</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">de Luis DA, Pacheco D, Izaola O, et al. Micronutrient status in morbidly obese women before bariatric surgery. Surg Obes Relat Dis. 2013;9(2):323-327. DOI:10.1016/j.soard.2011.09.015</mixed-citation><mixed-citation xml:lang="en">de Luis DA, Pacheco D, Izaola O, et al. Micronutrient status in morbidly obese women before bariatric surgery. Surg Obes Relat Dis. 2013;9(2):323-327. DOI:10.1016/j.soard.2011.09.015</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Lefebvre P, Letois F, Sultan A, et al. Nutrient deficiencies in patients with obesity considering bariatric surgery: a cross-sectional study. Surg Obes Relat Dis. 2014;10(3):540-546. DOI:10.1016/j.soard.2013.10.003</mixed-citation><mixed-citation xml:lang="en">Lefebvre P, Letois F, Sultan A, et al. Nutrient deficiencies in patients with obesity considering bariatric surgery: a cross-sectional study. Surg Obes Relat Dis. 2014;10(3):540-546. DOI:10.1016/j.soard.2013.10.003</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Бодунова Н.А., Аскерханов Р.Г., Хатьков И.Е., и др. Влияние бариатрических операций на обмен витаминов у больных ожирением. // Терапевтический архив. — 2015. — Т. 87. — №2. — C. 70-76. [Bodunova NA, Askerkhanov RG, Khat’kov IE, et al. Impact of bariatric surgery on vitamin metabolisms in obese patients. Ter Arkh. 2015;87(2):70-76. (In Russ).] DOI:10.17116/terarkh201587270-76</mixed-citation><mixed-citation xml:lang="en">Бодунова Н.А., Аскерханов Р.Г., Хатьков И.Е., и др. Влияние бариатрических операций на обмен витаминов у больных ожирением. // Терапевтический архив. — 2015. — Т. 87. — №2. — C. 70-76. [Bodunova NA, Askerkhanov RG, Khat’kov IE, et al. Impact of bariatric surgery on vitamin metabolisms in obese patients. Ter Arkh. 2015;87(2):70-76. (In Russ).] DOI:10.17116/terarkh201587270-76</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Мельниченко Г.А., Шестакова М.В., и др. Национальные клинические рекомендации по лечению морбидного ожирения у взрослых. 3-ий пересмотр (лечение морбидного ожирения у взрослых). // Ожирение и метаболизм. — 2018. — Т. 15. — №1. — С. 53-70. [Dedov II, Mel’nichenko GA, Shestakova MV, et al. Russian national clinical recommendations for morbid obesity treatment in adults. 3rd revision (Morbid obesity treatment in adults). Obesity and metabolism. 2018;15(1):53-70. (In Russ).] DOI:10.14341/OMET2018153-70</mixed-citation><mixed-citation xml:lang="en">Дедов И.И., Мельниченко Г.А., Шестакова М.В., и др. Национальные клинические рекомендации по лечению морбидного ожирения у взрослых. 3-ий пересмотр (лечение морбидного ожирения у взрослых). // Ожирение и метаболизм. — 2018. — Т. 15. — №1. — С. 53-70. [Dedov II, Mel’nichenko GA, Shestakova MV, et al. Russian national clinical recommendations for morbid obesity treatment in adults. 3rd revision (Morbid obesity treatment in adults). Obesity and metabolism. 2018;15(1):53-70. (In Russ).] DOI:10.14341/OMET2018153-70</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Parrott J, Frank L, Rabena R, et al. American Society for Metabolic and Bariatric Surgery Integrated Health Nutritional Guidelines for the Surgical Weight Loss Patient 2016 Update: Micronutrients. Surg Obes Relat Dis. 2017;13(5):727-741. DOI:10.1016/j.soard.2016.12.018</mixed-citation><mixed-citation xml:lang="en">Parrott J, Frank L, Rabena R, et al. American Society for Metabolic and Bariatric Surgery Integrated Health Nutritional Guidelines for the Surgical Weight Loss Patient 2016 Update: Micronutrients. Surg Obes Relat Dis. 2017;13(5):727-741. DOI:10.1016/j.soard.2016.12.018</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Busetto L, Dicker D, Azran C, et al. Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management. Obes Facts. 2017;10(6):597-632. DOI:10.1159/000481825</mixed-citation><mixed-citation xml:lang="en">Busetto L, Dicker D, Azran C, et al. Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management. Obes Facts. 2017;10(6):597-632. DOI:10.1159/000481825</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">O’Kane M, Pinkney J, Aasheim ET, et al. BOMSS Guidelines on peri-operative and postoperative biochemical monitoring and micronutrient replacement for patients undergoing bariatric surgery. BOMSS; 2014.</mixed-citation><mixed-citation xml:lang="en">O’Kane M, Pinkney J, Aasheim ET, et al. BOMSS Guidelines on peri-operative and postoperative biochemical monitoring and micronutrient replacement for patients undergoing bariatric surgery. BOMSS; 2014.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Mechanick JI, Kushner RF, Sugerman HJ, et al. American Association of Clinical Endocrinologists, The Obesity Society, American Society for Metabolic &amp; Bariatric Surgery: Medical guidelines for clinical practice for the perioperative nutritional, metabolic, and non surgical support of the bariatric surgery patient. Surg Obes Relat Dis. 2008;4(5 Suppl):S109-184. DOI:10.1016/j.soard.2008.08.009</mixed-citation><mixed-citation xml:lang="en">Mechanick JI, Kushner RF, Sugerman HJ, et al. American Association of Clinical Endocrinologists, The Obesity Society, American Society for Metabolic &amp; Bariatric Surgery: Medical guidelines for clinical practice for the perioperative nutritional, metabolic, and non surgical support of the bariatric surgery patient. Surg Obes Relat Dis. 2008;4(5 Suppl):S109-184. DOI:10.1016/j.soard.2008.08.009</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Parkes E. Nutritional Management of Patients after Bariatric Surgery. Am J Med Sci. 2006;331(4):207-213. DOI:10.1097/00000441-200604000-00007</mixed-citation><mixed-citation xml:lang="en">Parkes E. Nutritional Management of Patients after Bariatric Surgery. Am J Med Sci. 2006;331(4):207-213. DOI:10.1097/00000441-200604000-00007</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Malinowski SS. Nutritional and Metabolic Complications of Bariatric Surgery. Am J Med Sci. 2006;331(4):219-225. DOI:10.1097/00000441-200604000-00009</mixed-citation><mixed-citation xml:lang="en">Malinowski SS. Nutritional and Metabolic Complications of Bariatric Surgery. Am J Med Sci. 2006;331(4):219-225. DOI:10.1097/00000441-200604000-00009</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Love AL, Billett HH. Obesity, bariatric surgery, and iron deficiency: True, true, true and related. Am J Hematol. 2008;83(5):403-409. DOI:10.1002/ajh.21106</mixed-citation><mixed-citation xml:lang="en">Love AL, Billett HH. Obesity, bariatric surgery, and iron deficiency: True, true, true and related. Am J Hematol. 2008;83(5):403-409. DOI:10.1002/ajh.21106</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Wax JR, Pinette MG, Cartin A, Blackstone J. Female reproductive issues following bariatric surgery. Obstet Gynecol Surv. 2007;62(9):595-604. DOI:10.1097/01.ogx.0000279291.86611.46</mixed-citation><mixed-citation xml:lang="en">Wax JR, Pinette MG, Cartin A, Blackstone J. Female reproductive issues following bariatric surgery. Obstet Gynecol Surv. 2007;62(9):595-604. DOI:10.1097/01.ogx.0000279291.86611.46</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Marinella MA. Anemia following Roux-en-Y surgery for morbid obesity: a review. South Med J. 2008;101(10):1024-1031. DOI:10.1097/SMJ.0b013e31817cf7b7</mixed-citation><mixed-citation xml:lang="en">Marinella MA. Anemia following Roux-en-Y surgery for morbid obesity: a review. South Med J. 2008;101(10):1024-1031. DOI:10.1097/SMJ.0b013e31817cf7b7</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Cancelo-Hidalgo MJ, Castelo-Branco C, Palacios S, et al. Tolerability of different oral iron supplements: a systematic review. Curr Med Res Opin. 2013;29(4):291-303. DOI:10.1185/03007995.2012.761599</mixed-citation><mixed-citation xml:lang="en">Cancelo-Hidalgo MJ, Castelo-Branco C, Palacios S, et al. Tolerability of different oral iron supplements: a systematic review. Curr Med Res Opin. 2013;29(4):291-303. DOI:10.1185/03007995.2012.761599</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Беловол А.Н., Князькова И.И. От метаболизма железа – к вопросам фармакологической коррекции его дефицита. // Ліки України. — 2015. — №4. — С. 46-51. [Bilovol AN, Knyaz’kova II. From Iron Metabolism to the Issues of Pharmacological Correction of Iron Deficiency. Liky Ukrai’ny. 2015;(4):46-51. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Беловол А.Н., Князькова И.И. От метаболизма железа – к вопросам фармакологической коррекции его дефицита. // Ліки України. — 2015. — №4. — С. 46-51. [Bilovol AN, Knyaz’kova II. From Iron Metabolism to the Issues of Pharmacological Correction of Iron Deficiency. Liky Ukrai’ny. 2015;(4):46-51. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Trailokya A, Srivastava A, Bhole M, Zalte N. Calcium and Calcium Salts. J Assoc Physicians India. 2017;65(2):100-103.</mixed-citation><mixed-citation xml:lang="en">Trailokya A, Srivastava A, Bhole M, Zalte N. Calcium and Calcium Salts. J Assoc Physicians India. 2017;65(2):100-103.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Громова О.А., Торшин И.Ю., Гоголева И.В., и др. Органические соли кальция: перспективы использования в клинической практике. // РМЖ. — 2012. — Т. 20. — №28. — С. 1407-1411. [Gromova OA, Torshin IY, Gogoleva IV, et al. Organicheskie soli kal’tsiya: perspektivy ispol’zovaniya v klinicheskoy praktike. RMZh. 2012;20(28):1407-1411. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Громова О.А., Торшин И.Ю., Гоголева И.В., и др. Органические соли кальция: перспективы использования в клинической практике. // РМЖ. — 2012. — Т. 20. — №28. — С. 1407-1411. [Gromova OA, Torshin IY, Gogoleva IV, et al. Organicheskie soli kal’tsiya: perspektivy ispol’zovaniya v klinicheskoy praktike. RMZh. 2012;20(28):1407-1411. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Tondapu P, Provost D, Adams-Huet B, et al. Comparison of the absorption of calcium carbonate and calcium citrate after Roux-en-Y gastric bypass. Obes Surg. 2009;19(9):1256-1261. DOI:10.1007/s11695-009-9850-6</mixed-citation><mixed-citation xml:lang="en">Tondapu P, Provost D, Adams-Huet B, et al. Comparison of the absorption of calcium carbonate and calcium citrate after Roux-en-Y gastric bypass. Obes Surg. 2009;19(9):1256-1261. DOI:10.1007/s11695-009-9850-6</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Доброхотова Ю.Э., Дугиева М.З. Постменопаузальный остеопороз: препараты кальция в современной стратегии профилактики и лечения. // РМЖ. Мать и дитя. — 2017. — Т. 25. — №15. — С. 1135-1139. [Dobrohotova YE, Dugieva MZ. Postmenopauzal’nyy osteoporoz: preparaty kal’tsiya v sovremennoy strategii profilaktiki i lecheniya. RMZh. Mat’ i ditya. 2017;25(15):1135-1139. (In Russ).]</mixed-citation><mixed-citation xml:lang="en">Доброхотова Ю.Э., Дугиева М.З. Постменопаузальный остеопороз: препараты кальция в современной стратегии профилактики и лечения. // РМЖ. Мать и дитя. — 2017. — Т. 25. — №15. — С. 1135-1139. [Dobrohotova YE, Dugieva MZ. Postmenopauzal’nyy osteoporoz: preparaty kal’tsiya v sovremennoy strategii profilaktiki i lecheniya. RMZh. Mat’ i ditya. 2017;25(15):1135-1139. (In Russ).]</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Sakhaee K, Bhuket T, Adams-Huet B, Rao DS. Meta–analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate. Am J Ther. 1999;6(6):313-321. DOI:10.1097/00045391-199911000-00005</mixed-citation><mixed-citation xml:lang="en">Sakhaee K, Bhuket T, Adams-Huet B, Rao DS. Meta–analysis of calcium bioavailability: a comparison of calcium citrate with calcium carbonate. Am J Ther. 1999;6(6):313-321. DOI:10.1097/00045391-199911000-00005</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Allied Health Sciences Section Ad Hoc Nutrition C, Aills L, Blankenship J, et al. ASMBS Allied Health Nutritional Guidelines for the Surgical Weight Loss Patient. Surg Obes Relat Dis. 2008;4(5 Suppl):S73-108. DOI:10.1016/j.soard.2008.03.002</mixed-citation><mixed-citation xml:lang="en">Allied Health Sciences Section Ad Hoc Nutrition C, Aills L, Blankenship J, et al. ASMBS Allied Health Nutritional Guidelines for the Surgical Weight Loss Patient. Surg Obes Relat Dis. 2008;4(5 Suppl):S73-108. DOI:10.1016/j.soard.2008.03.002</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Koch TR, Finelli FC. Postoperative metabolic and nutritional complications of bariatric surgery. Gastroenterol Clin North Am. 2010;39(1):109-124. DOI:10.1016/j.gtc.2009.12.003</mixed-citation><mixed-citation xml:lang="en">Koch TR, Finelli FC. Postoperative metabolic and nutritional complications of bariatric surgery. Gastroenterol Clin North Am. 2010;39(1):109-124. DOI:10.1016/j.gtc.2009.12.003</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
