ometendoОжирение и метаболизмObesity and metabolism2071-87132306-5524Endocrinology Research Centre10.14341/omet10037ometendo-10037Research ArticleОбзор литературыReviewОвариальный резерв и аутоиммунные заболевания щитовидной железыOvarian reserve and autoimmune thyroid diseaseshttps://orcid.org/0000-0003-4979-7420ГригорянОльга РафаэльевнаGrigoryanOlga R.

профессор, доктор медицинских наук, главный научный сотрудник

 

MD, Professor

 

iceberg1995@mail.ruhttps://orcid.org/0000-0002-2683-9387КрасновскаяНаталья СергеевнаKrasnovskayaNatal'ya S.

Врач-эндокринолог отделения эндокринологии

 

MD, Department of Endocrinology

krasnovskayaNS@yandex.ruhttps://orcid.org/0000-0001-5826-3186МихеевРоберт КонстантиновичMikheevRobert K.

Студент

 

medical student

 

mikheev-robert@list.ruhttps://orcid.org/0000-0002-7563-5356ЯроваяИрина СергеевнаYarovayaIrina S.

Врач акушер-гинеколог, эндокринолог, кандидат медицинских наук, врач высшей квалификационной категории

MD, PhD

yarovaya.is@yandex.ruhttps://orcid.org/0000-0001-8425-0020АндрееваЕлена НиколаевнаAndreevaElena N.

Заведующая отделением эндокринной гинекологии. Профессор, доктор медицинских наук, врач высшей квалификационной категории

 

MD, Professor

 

 

gynec@endocrincentr.ruhttps://orcid.org/0000-0002-8175-7886ДедовИван ИвановичDedovIvan I.

Директор Центра, Член Президиума РАН, академик, доктор медицинских наук, профессор, Президент Российской ассоциации эндокринологов, главный внештатный специалист-эксперт эндокринолог Министерства здравоохранения России

 

MD, PhD, professor

dedov@endocrincentr.ru<p>ФГБУ &laquo;Национальный медицинский исследовательский центр эндокринологии&raquo; Минздрава России</p>Россия<p>Endocrinology Research Centre</p>Russian Federation<p>ГБУЗ &laquo;Городская поликлиника №9&raquo; Департамента здравоохранения города Москвы</p>Россия<p>City polyclinic №9 of the Moscow Health Department</p>Russian Federation<p>ФГБОУ ВО &laquo;Московский государственный медико-стоматологический университет имени А.И. Евдокимова&raquo; Минздрава России</p>Россия<p>A.I. Yevdokimov Moscow State University of Medicine and Dentistry</p>Russian Federation2019160920191621621Copyright &#x00A9; Григорян О.Р., Красновская Н.С., Михеев Р.К., Яровая И.С., Андреева Е.Н., Дедов И.И., 20192019Григорян О.Р., Красновская Н.С., Михеев Р.К., Яровая И.С., Андреева Е.Н., Дедов И.И.Grigoryan O.R., Krasnovskaya N.S., Mikheev R.K., Yarovaya I.S., Andreeva E.N., Dedov I.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.omet-endojournals.ru/jour/article/view/10037

В обзоре представлена информация о клинических исследованиях, в которых оценивалась связь носительства антитиреоидных антител (АТА) и состояния овариального резерва, а также эффективности вспомогательных репродуктивных технологий. Неоднозначность, а порой и противоположность выводов разных авторов позволяет рекомендовать взвешенно относиться к целесообразности скринингового обследования на АТА у женщин с нарушением репродуктивной функции, а также к предлагаемым в некоторых руководствах лечебным мероприятиям, основанным на результатах такого обследования.

Present literature review provides information about clinical trials that evaluated the association of the carriage of antithyroid antibodies (ATA) and the reduction of the ovarian reserve, as well as the effectiveness of assisted reproductive technologies. The ambiguity and sometimes the opposite of the conclusions of different authors, makes it possible to recommend a balanced attitude to the advisability of screening for ATA in women with a reproductive dysfunction as well as the therapeutic measures proposed in some guidelines based on the results of such examination.

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The authors declare that there are no conflicts of interest present.